化工社化工社 化学情報印刷レポート · 研究参考用
Ethylenediaminetetraacetic Acid → 3-Hydroxy-2-naphthoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethylenediaminetetraacetic Acid | HCID 6049 | — |
| 反応物 | 2-Naphthol | HCID 8663 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | [2-adenin-9-yl-5-[[[[5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl]oxy-oxido-phosphoryl]oxymethyl]-4-hydroxy-tetrahydrofuran-3-yl] phosphate | HCID 12598259 | — |
| 生成物 | 3-Hydroxy-2-naphthoic acid | HCID 7104 | 74% |
反応手順
An autoclave equipped with stirrer is charged with 1,240 parts of β-naphthol, 608 parts of aqueous sodium hydroxide solution (50% strength by weight), 27 parts of aqueous potassium hydroxide solution (85% strength by weight) and 12 parts of the tetrasodium salt of ethylenediaminetetraacetic acid (dissolved in 50 parts of water). The charge is mixed thoroughly under nitrogen and heated until the internal temperature reaches 260° C. 520 parts of 2-hydroxy-naphthalene-3-carboxylic acid (corresponding to 74% of theory, based on β-naphthol converted) are obtained analogously to Example 1. The proportion of resin formed is 11 mole percent, based on β-naphthol employed. 700 parts of β-naphthol are recovered.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04002675 |
| 出典データセット | uspto-grants-1977_01 |
| ORD ID | ord-1bee5b8bb4bc44dfabede97266695dd4 |
| 出典メモ | uspto-grants-1977_01 |