反応式
N[C:2]1[C:3]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])=[N:4][CH:5]=[CH:6][CH:7]=1.N([O-])=O.[Na+].[ClH:17]>>[Cl:17][C:2]1[C:3]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])=[N:4][CH:5]=[CH:6][CH:7]=1参加物
3
実験手順
(a) Reaction of 3-amino-2-(4-aminobutyl)pyridine with sodium nitrite/hydrochloric acid and treatment of the resultant diazonium salt with cuprous chloride yields 3-chloro-2-(4-aminobutyl)pyridine. By a similar procedure employing cuprous bromide and hydrobromic acid 3-bromo-2-(4-aminobutyl)pyridine may be produced and when the diazonium salt is treated with sulphuric acid the product is 3-hydroxy-2-(4-aminobutyl)pyridine.
出典と根拠
- ORDレコード
- ord-921fbe9b334e49e4bd0217e1d0dea12c
- 出典データセット
- uspto-grants-1977_01
- 特許番号
- US04002759
関連ノート
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