Hydrochloric Acid → HCID 54124309、化合物

HRID 1415220ノート

反応式

HRID 1415220 の反応式
[C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])(=[O:3])[CH3:2].[OH:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH:15]=O.N1CCOCC1.Cl>O.C(O)C>[OH:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH:15]=[CH:2][C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])=[O:3]

参加物

7

反応物 4

HCID 313Hydrochloric AcidHCID 8083MorpholineHCID 12127IsovanillinHCID 3364732-Acetyl-1,3-cyclopentanedione

生成物 1

HCID 54124309HCID 54124309、化合物

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

実験手順

2-Acetyl-1,3-cyclopentanedione (3.83 g.) was treated with 5.0 g. of 3-hydroxy-4-methoxybenzaldehyde in 120 ml. of ethanol in the presence of 5 ml. of morpholine under reflux for 5 hours. After cooling, the reaction mixture was poured into 200 ml. of water containing 8 ml. of conc. hydrochloric acid. Deposited crystals were separated by filtration, washed with water and ethanol successively, and dried. 2-(3-Hydroxy-4-methoxycinnamoyl)-1,3-cyclopentanedione (5.46 g.) was obtained, in the form of yellow crystals which showed mp. 137°-139° C. after recrystallisation from a mixed solvent of ethanol and dioxane.

後処理

  1. temperatureAfter cooling
  2. additionthe reaction mixture was poured into 200 ml
  3. customDeposited crystals were separated by filtration
  4. washwashed with water and ethanol successively
  5. customdried

出典と根拠

ORDレコード
ord-c103825e3ccf495bbd7a3369715b113d
出典データセット
uspto-grants-1977_01
特許番号
US04003936

反応ノート

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