4-Nitro-3-(trifluoromethyl)benzenesulfonamide → HCID 21482732、化合物
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([NH2:13])(=[O:12])=[O:11])=[CH:6][C:5]=1[C:14]([F:17])([F:16])[F:15])([O-])=O.[H][H]>[Ru].C(O)C>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([S:10]([NH2:13])(=[O:11])=[O:12])=[CH:6][C:5]=1[C:14]([F:17])([F:15])[F:16]参加物
5
実験手順
1.0 G. of 4-nitro-3-trifluoromethylbenzenesulfonamide is hydrogenated over 5% Ruthenium on charcoal in 20 ml. of absolute ethanol at room temperature under 40 lbs. of hydrogen for 5 hours. The hydrogen uptake is 100% of theory. The mixture is filtered, evaporated and dried affording 0.87 g. of crude solid. This material is recrystallized from toluene affording 0.75 g. of 4-amino-3-trifluoromethylbenzenesulfonamide, m.p. 150° to 151° C.
後処理
- customat room temperature
- filtrationThe mixture is filtered
- customevaporated
- customdried
- customaffording 0.87 g
- customThis material is recrystallized from toluene affording 0.75 g
出典と根拠
- ORDレコード
- ord-03ce45c2874041ceb4b3f1deddd963eb
- 出典データセット
- uspto-grants-1977_01
- 特許番号
- US04005199
反応ノート
読み込み中…