Ethylenediamine → N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-ethylenediamine

HRID 1415537

反応式

HRID 1415537 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:11][O:10]2)=[CH:5][CH:4]=1.[CH2:12]([NH2:15])[CH2:13][NH2:14]>CO.O>[OH:10][CH:9]([C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)[CH2:11][NH:14][CH2:13][CH2:12][NH2:15]

参加物

5

反応物 2

HCID 3301EthylenediamineHCID 980482-(4-Methoxyphenyl)oxirane

生成物 1

HCID 21482929N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-ethylenediamine

試薬・触媒・溶媒 2

HCID 887Methanol溶媒2 回HCID 962Water溶媒

実験手順

N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-ethylenediamine is prepared by reacting 2-(4-methoxyphenyl)oxirane (37.5 g.) dissolved in methanol (52 cc.) with ethylenediamine (30 cc.) dissolved in a mixture of methanol (52 cc.) and water (20 cc.). On distillation under reduced pressure, a product (22.3 g.), b.p. 165°-169° C./0.2 mm.Hg, is obtained, which crystallises on cooling and melts at 68° C.

後処理

  1. distillationOn distillation under reduced pressure
  2. customa product (22.3 g.), b.p. 165°-169° C./0.2 mm.Hg, is obtained
  3. customwhich crystallises
  4. temperatureon cooling

出典と根拠

ORDレコード
ord-8e3fe7b98a9543bcb984cc75cb887cb4
出典データセット
uspto-grants-1977_01
特許番号
US04005212

関連ノート

読み込み中…