Hydrochloric Acid → 1-Methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea hydrochloride

反応式

[CH3:1][O:2][C:3]([NH:5][C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH:15][C:16](=[O:21])[CH2:17][N:18]([CH3:20])[CH3:19])=[S:7])=[O:4].[ClH:22]>C(O)C.C(OCC)C>[ClH:22].[CH3:1][O:2][C:3]([NH:5][C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH:15][C:16](=[O:21])[CH2:17][N:18]([CH3:20])[CH3:19])=[S:7])=[O:4]

参加物

実験手順

1-Methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea (3.0 g) was dissolved in the minimum quantity of ethanol and the solution treated with diethyl ether (300 ml), followed by an excess of a saturated solution of hydrogen chloride in diethyl ether. The resultant solid was filtered off and recrystallised from ethanol to give 1-methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea hydrochloride (2.8 g) m.p. 187°-188° C. (with decomposition).