Cephalexin Monohydrate → Cephalexin sodium salt

HRID 1415708

反応式

HRID 1415708 の反応式
[CH3:1][C:2]1[CH2:21][S:20][C@@H:5]2[C@H:6]([NH:9][C:10]([C@H:12]([NH2:19])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[O:11])[C:7](=[O:8])[N:4]2[C:3]=1[C:22]([OH:24])=[O:23].O.C(=O)(O)[O-].[Na+:30]>O>[CH3:1][C:2]1[CH2:21][S:20][C@@H:5]2[C@H:6]([NH:9][C:10]([C@H:12]([NH2:19])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[O:11])[C:7](=[O:8])[N:4]2[C:3]=1[C:22]([O-:24])=[O:23].[Na+:30]

参加物

4

反応物 2

HCID 62921Cephalexin MonohydrateHCID 516892Sodium Bicarbonate

生成物 1

HCID 23667618Cephalexin sodium salt収率 95%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

25 gms of cephalexin monohydrate was suspended in 75 ml of water. To this under stirring, 5.75 gms of sodium bicarbonate was added. The solution were filtered and lyophilized to afford 24 gms of crystalline cephalexin sodium.

後処理

  1. filtrationThe solution were filtered

出典と根拠

ORDレコード
ord-65e39593c25049fb9aaf2b8d7e339214
出典データセット
uspto-grants-1999_06
特許番号
US05908929

関連ノート

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