1-(4-Methoxyphenyl)-4-Methyl-2-(4-sulfamoylphenyl)pyrrole → 3-Benzoylpropionitrile

HRID 1415735

反応式

HRID 1415735 の反応式
Cl[C:2]1[CH:3]=[C:4]([C:10]2[N:11](C3C=C[C:19]([S:22](=O)(=O)N)=CC=3)[CH:12]=[C:13](C)[CH:14]=2)[CH:5]=[CH:6][C:7]=1OC.C[O:27][C:28]1[CH:33]=[CH:32][C:31]([N:34]2[CH:38]=[C:37]([CH3:39])[CH:36]=[C:35]2[C:40]2[CH:45]=[CH:44][C:43]([S:46](=[O:49])(=[O:48])[NH2:47])=[CH:42][CH:41]=2)=[CH:30][CH:29]=1>>[CH2:14]([CH2:13][C:12]#[N:11])[C:10]([C:4]1[CH:5]=[CH:6][CH:7]=[CH:2][CH:3]=1)=[O:27].[CH3:39][C:37]1[CH:36]=[C:35]([C:40]2[CH:45]=[CH:44][C:43]([S:46](=[O:49])(=[O:48])[NH2:47])=[CH:42][CH:41]=2)[N:34]([C:31]2[CH:32]=[CH:33][C:28]([S:22][CH3:19])=[CH:29][CH:30]=2)[CH:38]=1

参加物

4

反応物 2

HCID 218627931-(4-Methoxyphenyl)-4-Methyl-2-(4-sulfamoylphenyl)pyrroleHCID 218628462-(3-Chloro-4-methoxyphenyl)-4-methyl-1-(4-sulfamoylphenyl)pyrrole

生成物 2

HCID 1384653-BenzoylpropionitrileHCID 99287494-Methyl-1-(4-methylthiophenyl)-2-(4-sulfamoylphenyl)pyrrole

実験手順

In this Step, a phenacyl acetonitrile compound of formula (17) is prepared by alkylating the cyano compound of formula (16) with a phenacyl halide compound of formula (7). This reaction is essentially the same as and may be carried out in the same manner as and using the same reagents and reaction conditions as Step B3 of Method B.

後処理

  1. customthe same reagents and reaction conditions as Step B3 of Method B

出典と根拠

ORDレコード
ord-a257620a77224c62b266e2081366570a
出典データセット
uspto-grants-1999_06
特許番号
US05908858

関連ノート

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