5,6-Dimethylbenzimidazole → 1H-Furo[3,4-f]benzimidazole-5,7-dione
反応式
[N:1]1[C:5]2[CH:6]=[C:7]([C:13]([OH:15])=[O:14])[C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[NH:3][CH:2]=1.CC1C(C)=CC2N=CNC=2C=1>>[N:3]1[C:4]2[CH:9]=[C:8]3[C:10](=[O:12])[O:15][C:13](=[O:14])[C:7]3=[CH:6][C:5]=2[NH:1][CH:2]=1参加物
3
反応条件
- 温度
- 250 °C
実験手順
Benzimidazole-5,6-dicarboxylic acid (8.2 g), prepared from 5,6-dimethylbenzimidazole as described in J.Org.Chem. 1987, 52, 2934., was heated at 250° C. under vacuum (0.01 mm Hg) for 1 h. The solid was extracted with hot acetone and the acetone extracts were evaporated to give the title compound (6.1 g).
後処理
- extractionThe solid was extracted with hot acetone
- customthe acetone extracts were evaporated
出典と根拠
- ORDレコード
- ord-8d039b3793844ab9a102886c2463afb6
- 出典データセット
- uspto-grants-1999_06
- 特許番号
- US05912260
反応ノート
読み込み中…