Acetic Acid → HCID 67582831、化合物
反応式
[OH:1][CH2:2][CH2:3][O:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[N:8]=[C:7]([N:15]2[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]2)[N:6]=1.[C:21]([OH:24])(=[O:23])[CH3:22]>CO>[C:21]([OH:24])(=[O:23])[CH3:22].[OH:1][CH2:2][CH2:3][O:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[N:8]=[C:7]([N:15]2[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]2)[N:6]=1参加物
4
実験手順
To a solution of 4-[(2-hydroxyethyl)oxy]-2-(1-piperazinyl)quinazoline (cf. Example 42) (1.2 g) in methanol (20 ml) is added acetic acid (0.3 g), and the mixture is evaporated to dryness under reduced pressure. The residue is recrystallized from acetonitrile to give 4-[(2-hydroxyethyl)oxy]-2-(1-piperazinyl)quinazoline monoacetate (0.2 g) as crystals.
後処理
- customthe mixture is evaporated to dryness under reduced pressure