Sodium Methoxide → 3-((1-methyl-2-(S)-pyrrolidinyl)methoxy)-5methoxy-pyridine-N-oxide
反応式
[CH3:1][N:2]1[CH2:6][CH2:5][CH2:4][C@H:3]1[CH2:7][O:8][C:9]1[CH:10]=[N+:11]([O-:16])[CH:12]=[C:13](Br)[CH:14]=1.[CH3:17][O-:18].[Na+]>CO>[CH3:1][N:2]1[CH2:6][CH2:5][CH2:4][C@H:3]1[CH2:7][O:8][C:9]1[CH:10]=[N+:11]([O-:16])[CH:12]=[C:13]([O:18][CH3:17])[CH:14]=1参加物
4
実験手順
A sample of the compound from step 98a above is reacted with sodium methoxide in methanol according to standard procedures. The reaction is quenched with water, the product is extracted, then purified by chromatography on silica gel.
後処理
- customThe reaction is quenched with water
- extractionthe product is extracted
- custompurified by chromatography on silica gel
出典と根拠
- ORDレコード
- ord-1d450716c2c64c538c2ac86dc76cce6f
- 出典データセット
- uspto-grants-1999_06
- 特許番号
- US05914328
反応ノート
読み込み中…