HCID 9837522、化合物 → HCID 21845565、化合物

HRID 1417289ノート

反応式

HRID 1417289 の反応式
[NH2:1][C:2](=[S:14])[NH:3][S:4]([C:7]1[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][CH:8]=1)(=[O:6])=[O:5].Br[CH2:16][C:17]([C:19]1[CH:24]=[C:23]([N+:25]([O-:27])=[O:26])[C:22]([OH:28])=[C:21]([OH:29])[CH:20]=1)=O>C(O)C>[OH:29][C:21]1[CH:20]=[C:19]([C:17]2[N:1]=[C:2]([NH:3][S:4]([C:7]3[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][CH:8]=3)(=[O:5])=[O:6])[S:14][CH:16]=2)[CH:24]=[C:23]([N+:25]([O-:27])=[O:26])[C:22]=1[OH:28]

参加物

4

反応物 2

HCID 9837522HCID 9837522、化合物HCID 218455962-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone

生成物 1

HCID 21845565HCID 21845565、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 0.24 g of N-(aminothioxomethyl)-4-methyl-benzenesulfonamide and 0.2 g of 2-bromo-1-(3,4-dihydroxy-5-nitrophenyl)ethanone was dissolved in 5 ml of ethanol and boiled under reflux for 1 h. 0.26 g of N-[4-(3,4-dihydroxy-5-nitro-phenyl)-thiazol-2-yl]-4-methyl-benzenesulfonamide separated as red crystals upon cooling.

後処理

  1. temperatureunder reflux for 1 h
  2. custom0.26 g of N-[4-(3,4-dihydroxy-5-nitro-phenyl)-thiazol-2-yl]-4-methyl-benzenesulfonamide separated as red crystals
  3. temperatureupon cooling

出典と根拠

ORDレコード
ord-53a0b64789e24a0a8379b511b3f947b8
出典データセット
uspto-grants-1999_03
特許番号
US05877193

反応ノート

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