Hydrazine → HCID 16105140、化合物
反応式
[N+:1]([C:4]1[CH:25]=[CH:24][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]2C(=O)C3C(=CC=CC=3)C2=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].NN>C(O)C>[N+:1]([C:4]1[CH:25]=[CH:24][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][NH2:13])=[CH:6][CH:5]=1)([O-:3])=[O:2]参加物
4
実験手順
A suspension of 62.6 g of 2-[4-(4-nitrophenoxy)butyl]-1H-isoindole-1,3(2H)-dione (Example 33) in one liter of ethanol is treated with 6.5 ml of hydrazine, and the mixture then stirred at reflux for 18 hours. After cooling to room temperature, the precipitate is collected, washed with 250 ml of hot 2.5N HCl, and 200 ml of hot H2O. The combined acid and water washes are taken to dryness to obtain the hydrochloride salt of the title compound. Mass spectrometry shows the presence of the title compound. The compound is utilized directly without further purification.