Glycinamide → HCID 54569709、化合物

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[N:9]=[C:10]=[S:11].[NH2:12][CH2:13][C:14]([NH2:16])=[O:15]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10](=[S:11])[NH:12][CH2:13][C:14]([NH2:16])=[O:15]

参加物

反応物 2

HCID 69020Glycinamide

HCID 1232391,3-Dichloro-2-isothiocyanatobenzene

生成物 1

HCID 54569709HCID 54569709、化合物

実験手順

2-[3-(2,6-Dichlorophenyl)-thioureido]-acetamide was prepared by the procedure described in Example 2 using 40.8 g of 2,6-dichlorophenyl-isothiocyanate and 29.6 g of glycinamide. The product was obtained (54 g) as a solid, m.p. 189°-191° C. Mass spectrum (+FAB, [M+H]+) m/z 278/280/282. This intermediate was used in the next paragraph without further purification.

後処理

customThe product was obtained (54 g) as a solid, m.p. 189°-191° C
customThis intermediate was used in the next paragraph without further purification

出典と根拠

ORDレコード: ord-d529689878f54aaf88a86a21daa3a62d
出典データセット: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05877324

反応ノート

読み込み中…

参加物