化工社化工社 化学情報印刷レポート · 研究参考用
Glycine → Glycine, N-dodecyl-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Glycine | HCID 750 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 1-Bromododecane | HCID 8919 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | Glycine, N-dodecyl- | HCID 16771 | 26.3% |
反応手順
Glycine was dissolved in a 2:1 mixture by volume of IPA and water. Triethylamine and 1-bromododecane were added to the solution successively and the mixture was kept stirring for more than 7 days. After the solvent was removed, THF was added to the remaining material. Triethylamine hydrobromide was removed by filtration and the filtrate was concentrated. N-n-dodecylglycine was obtained from the concentrated solution by separation and purification by column chromatography with the yield of 26.3%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | USRE036138 |
| 出典データセット | uspto-grants-1999_03 |
| ORD ID | ord-a94051af64e743c9a743f87c0b107717 |
| 出典メモ | uspto-grants-1999_03 |