4-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyran → 4-cyano-4-(3-triisopropylsilylthiophenyl)-3,4,5,6-tetrahydro-2H-pyran

HRID 1418496

反応式

HRID 1418496 の反応式
[C:1]([C:3]1([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([S:16][Si:17]([CH:24]([CH3:26])[CH3:25])([CH:21]([CH3:23])[CH3:22])[CH:18]([CH3:20])[CH3:19])[CH:11]=2)[CH2:8][CH2:7][O:6][CH:5](C)[CH2:4]1)#[N:2].C(C1(C2C=CC=C(I)C=2)CCOCC1)#N>>[C:1]([C:3]1([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([S:16][Si:17]([CH:21]([CH3:23])[CH3:22])([CH:24]([CH3:26])[CH3:25])[CH:18]([CH3:19])[CH3:20])[CH:11]=2)[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1)#[N:2]

参加物

3

反応物 2

HCID 117713774-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyranHCID 18786333(2SR,4RS)-4-cyano-2-methyl-4-(3-triisopropylsilylthiophenyl)-3,4,5,6-tetrahydro-2H-pyran

生成物 1

HCID 113608724-cyano-4-(3-triisopropylsilylthiophenyl)-3,4,5,6-tetrahydro-2H-pyran

実験手順

The titled compound was prepared according to the procedure described in example 29C for the preparation of (2SR,4RS)-4-cyano-2-methyl-4-(3-triisopropylsilylthiophenyl)-3,4,5,6-tetrahydro-2H-pyran using 4-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyran in place of (2SR,4RS)-4-cyano-4-(3-iodophenyl)-2-methyl-3,4,5,6-tetrahydro-2H-pyran.

出典と根拠

ORDレコード
ord-a510672ef87245bba103222d130fd591
出典データセット
uspto-grants-1999_03
特許番号
US05883106

関連ノート

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