3-Methoxyphenyl isocyanate → N-(2-hydroxy-4-nitrophenyl)-N'-(3-methoxyphenyl)urea

HRID 1419357ノート

反応式

HRID 1419357 の反応式
[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([N:20]=[C:21]=[O:22])[CH:17]=[CH:18][CH:19]=1>>[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH:4][C:21]([NH:20][C:16]1[CH:17]=[CH:18][CH:19]=[C:14]([O:13][CH3:12])[CH:15]=1)=[O:22]

参加物

3

反応物 2

HCID 878433-Methoxyphenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

生成物 1

HCID 21184674N-(2-hydroxy-4-nitrophenyl)-N'-(3-methoxyphenyl)urea収率 46.2%

実験手順

N-(2-Hydroxy-4-nitrophenyl)-N'-(3-methoxyphenyl)urea was prepared from 2-hydroxy 4-nitro aniline (154 mg, 1.0 mmol) and 3-methoxy phenyl isocyanate(1.0 mmol) according to the procedure in General Method B. The product was purified by dilution with methylene chloride and precipitation with hexanes. Filtering afforded the title compound (140 mg, 46%). EI-MS m/z 302(M-H)-

後処理

  1. customThe product was purified by dilution with methylene chloride and precipitation with hexanes
  2. filtrationFiltering

出典と根拠

ORDレコード
ord-d0f4bdd00bc24dfaa35a8c2b0121b294
出典データセット
uspto-grants-1999_03
特許番号
US05886044

反応ノート

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