Hydrochloric Acid → HCID 178429772、化合物
反応式
[CH3:1][C:2]1([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.Cl.[H][H]>CO.[Rh]>[CH3:1][C:2]1([C@@H:8]2[CH2:9][CH2:10][C@H:11]([OH:14])[CH2:12][CH2:13]2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1参加物
6
実験手順
56.1 g (0.29 mol) of 4-(1-methylcyclohexyl)phenol (from 1-methylcyclohexene and phenol in accordance with Chem. Ber. 57 (1924) 857) in 200 ml of methanol to which 1 ml of concentrated hydrochloric acid had been added were hydrogenated at 50° C. with 150 bar of hydrogen in the presence of 5 g of rhodium (5% on charcoal). After removal of the catalyst by filtration with suction, and concentration, 56.1 g (98.5% of theory) remained of an almost pure cis alcohol as a colorless solid.
後処理
- customAfter removal of the catalyst
- filtrationby filtration
- concentrationwith suction, and concentration, 56.1 g (98.5% of theory)
出典と根拠
- ORDレコード
- ord-41926dadd8f34fad923e195389379f30
- 出典データセット
- uspto-grants-1999_03
- 特許番号
- US05889012
反応ノート
読み込み中…