Nitromethane → HCID 9927343、化合物

HRID 1420772ノート

反応式

HRID 1420772 の反応式
Br[C:2]1[CH:9]=[C:8]2[N:4]([C:5]3[C:13]([C:14]4[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=4)=[CH:12][S:11][C:6]=3[C:7]2=[O:10])[CH:3]=1.[OH-].[K+].[N+:24](C)([O-:26])=[O:25]>>[N+:24]([C:2]1[CH:9]=[C:8]2[N:4]([C:5]3[C:13]([C:14]4[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=4)=[CH:12][S:11][C:6]=3[C:7]2=[O:10])[CH:3]=1)([O-:26])=[O:25]

参加物

4

反応物 3

HCID 6375NitromethaneHCID 14797Potassium HydroxideHCID 9906877HCID 9906877、化合物

生成物 1

HCID 9927343HCID 9927343、化合物

実験手順

A solution of 1 mmol of the compound obtained in Example 12 in 50 ml of nitromethane is stirred for 12 hours at ambient temperature and the reaction mixture is then poured into a 1M potassium hydroxide solution. After extracting with dichloromethane, the organic phases are dried over sodium sulphate, filtered and concentrated under reduced pressure. Chromatography on silica gel (chloroform) allows the expected product to be isolated.

後処理

  1. extractionAfter extracting with dichloromethane
  2. dry with materialthe organic phases are dried over sodium sulphate
  3. filtrationfiltered
  4. concentrationconcentrated under reduced pressure
  5. customto be isolated

出典と根拠

ORDレコード
ord-725fbe83ab464311998c3e82eca88d25
出典データセット
uspto-grants-2000_06
特許番号
US06071945

反応ノート

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