2-Bromo-5-fluorophenol → 1-Bromo-2-(cyclopropylmethoxy)-4-fluorobenzene

反応式

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1[OH:9].Br[C:11]1([CH3:14])[CH2:13][CH2:12]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1[O:9][CH2:14][CH:11]1[CH2:13][CH2:12]1

参加物

反応物 2

HCID 27246002-Bromo-5-fluorophenol

HCID 148649461-Bromo-1-methylcyclopropane

生成物 1

HCID 668669451-Bromo-2-(cyclopropylmethoxy)-4-fluorobenzene

実験手順

Starting from commercially available 2-bromo-5-fluoro-phenol and commercially available bromo-methyl-cyclopropane the title compound is obtained as colorless oil after distillation at 5×103 mbar.

出典と根拠

ORDレコード: ord-71462668f47544dcb4f7a746028d9a4f
出典データセット: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08927557B2

反応ノート

読み込み中…