化工社化工社 化学情報印刷レポート · 研究参考用
2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole → 5-Ethyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole | HCID 68406043 | — |
| 溶媒 | Sulfuric Acid | HCID 1118 | — |
| 生成物 | 5-Ethyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde | HCID 86648487 | 29.1% |
反応手順
The same operation as in Example (33b) was performed using 2-(dimethoxymethyl)-5-ethyl-4-(trifluoromethyl)-1H-imidazole obtained in Example (39c) (about 4.09 mmol) and 2 N sulfuric acid (30 mL), to obtain 228.3 mg of the title compound as a white solid (29%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08927588B2 |
| 出典データセット | uspto-grants-2015_01 |
| ORD ID | ord-03458eee904b4081b6939b529f591f19 |
| 出典メモ | uspto-grants-2015_01 |