1-Isopropylhydrazine → 2-(propan-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine

HRID 1427371ノート

反応式

HRID 1427371 の反応式
CN(/[CH:4]=[C:5]1\[CH2:6][N:7](C(OC(C)(C)C)=O)[CH2:8][CH2:9][C:10]\1=O)C.[CH3:19][CH:20]([NH:22][NH2:23])[CH3:21]>>[CH3:19][CH:20]([N:22]1[CH:4]=[C:5]2[CH2:6][NH:7][CH2:8][CH2:9][C:10]2=[N:23]1)[CH3:21]

参加物

3

反応物 2

HCID 527891-IsopropylhydrazineHCID 10610967tert-butyl (3E)-3-[(dimethylamino)methylidene]-4-oxopiperidine-1-carboxylate

生成物 1

HCID 838631362-(propan-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine

実験手順

tert-Butyl (3E)-3-[(dimethylamino)methylidene]-4-oxopiperidine-1-carboxylate was condensed with propan-2-ylhydrazine; removal of the protecting group provided 2-(propan-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine.

後処理

  1. customremoval of the protecting group

出典と根拠

ORDレコード
ord-8e0c3e0b40ab4ef8afdc9a2de3d4f358
出典データセット
uspto-grants-2015_01
特許番号
US08933224B2

反応ノート

読み込み中…