Nitromethane → HCID 72709582、化合物
反応式
[Br:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8](=[O:11])[C:7]2=[O:12].[N+:13]([CH3:16])([O-:15])=[O:14]>O>[Br:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8](=[O:11])[C:7]2([OH:12])[CH2:16][N+:13]([O-:15])=[O:14]参加物
4
反応条件
- 温度
- 30 °C
実験手順
7-bromoisatin (0.113 g) and nitromethane (0.15 ml) were added to water and the reaction mixture was vigorously stirred at a temperature of 30° C. for 24 hours. The obtained product was extracted with ethyl acetate and purified by silica gel column chromatography using ethyl acetate/hexane as eluents to afford pure product.
後処理
- extractionThe obtained product was extracted with ethyl acetate
- custompurified by silica gel column chromatography
- customto afford pure product
出典と根拠
- ORDレコード
- ord-8b35b516fb18404d89861cbda35430e2
- 出典データセット
- uspto-grants-2015_01
- 特許番号
- US08933248B2
反応ノート
読み込み中…