Mupirocin → ZE7Qpy4258
反応式
CC1(C)S[C@@H:5]2[C@H:7]([NH:10][C:11]([C@H:13](N)[C:14]3[CH:15]=[CH:16][C:17](O)=[CH:18][CH:19]=3)=O)[C:8](=O)N2[C@H]1C(O)=O.[CH2:26]1C(=O)[N:28]2[C@@H](C([O-])=O)/C(/O[C@H:27]12)=C/CO.[K+].C[C@@H:42]([C@@H](O)C)[C@@H:43]1O[C@H:44]1[CH2:46][C@@H:47]1[C@@H](O)[C@@H:51](O)[C@H:50]([CH2:55]/[C:56](/[CH3:72])=C/C(OCCCCCCCCC(O)=O)=O)[O:49][CH2:48]1.[CH:76]1C(NC(NC(NCCCCCCNC(NC(NC2C=CC(Cl)=CC=2)=N)=N)=N)=N)=CC=C(Cl)[CH:77]=1.C(O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O>>[CH3:26][C:27]1[C:5]2[CH2:76][CH2:77][N:10]([CH2:11][CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:7]=2[C:8]2[CH:51]=[C:50]([O:49][C:48]3[CH:42]=[CH:43][CH:44]=[CH:46][CH:47]=3)[CH:55]=[CH:56][C:72]=2[N:28]=1参加物
4
実験手順
Co-amoxiclav (1000/200 mg infusion, GlaxoSmithKline) was purchased from St George's NHS Hospital, London. Mupirocin was purchased from Sigma Aldrich Ltd (Poole, Dorset, UK). Chlorhexidine gluconate was purchased from Sigma Aldrich Ltd (Poole, Dorset, UK). 4-methyl-8-phenoxy-1-(2-phenylethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]quinoline (in hydrochloride salt form) was provided by Helperby Therapeutics.