関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | P-Cresol | HCID 2879 | — |
| 反応物 | Ethyl bromoacetate | HCID 7748 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | Ethyl (p-tolyloxy)acetate | HCID 4047281 | — |
反応手順
To a mixture of p-cresol (500 mg, 4.63 mmol) and ethyl 2-bromoacetate (928 mg, 5.56 mmol) in CH3CN (10 mL) was added K2CO3 (3 g, 21.7 mmol). The reaction mixture was stirred at 80° C. for 4 h. The solid was removed by filtration and the filtrate was concentrated to give the title compound which was used in the next step without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08940726B2 |
|---|
| 出典データセット | uspto-grants-2015_01 |
|---|
| ORD ID | ord-7b7fb5d4ae85490694cd2913b4151b63 |
|---|
| 出典メモ | uspto-grants-2015_01 |
|---|
