Ammonia → HCID 57417080、化合物
反応式
C[O:2][C:3]([C@@H:5]1[CH2:9][C@@H:8]([N:10]([CH3:12])[CH3:11])[CH2:7][NH:6]1)=O.[NH3:13]>CO>[CH3:11][N:10]([CH3:12])[C@H:8]1[CH2:7][NH:6][C@H:5]([C:3]([NH2:13])=[O:2])[CH2:9]1参加物
4
実験手順
A solution of (2S,4R)-4-Dimethylamino-pyrrolidine-2-carboxylic acid methyl ester (225 mg) and 7M ammonia in methanol (7 ml) is stood for 18 hours at room temperature in a sealed vessel. Evaporation and trituration with diethyl ether gives the title compound as a white solid.
後処理
- customEvaporation and trituration with diethyl ether
出典と根拠
- ORDレコード
- ord-495c0a1c47dc48d8af5a1916a15dcfce
- 出典データセット
- uspto-grants-2015_01
- 特許番号
- US08940771B2
反応ノート
読み込み中…