Phenylboronic Acid → 2-Cyano-3-fluorobiphenyl
反応式
[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6](I)[C:3]=1[C:4]#[N:5].[C:11]1(B(O)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.C1(C)C=CC=CC=1.CCO.O>COCCOC.O>[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:3]=1[C:4]#[N:5]参加物
5
実験手順
The desired product was prepared by substituting 2-fluoro-6-iodobenzonitrile for Example 1A and phenylboronic acid for Example 1B in Example 1C. Additionally, toluene/EtOH/H2O (3:2:1) was substituted for DME/H2O as the solvent.
出典と根拠
- ORDレコード
- ord-683e628802274827a95c8ef5670fba7a
- 出典データセット
- uspto-grants-2015_01
- 特許番号
- US08940778B2
反応ノート
読み込み中…