2-Dicyclohexylphosphino-2',4',6'-triisoprophylbiphenyl → 8-chloro-3-methyl-N-(5-morpholinopyridin-3-yl)-2-(pyridin-2-yl)quinolin-4-amine

反応式

C1(P(C2CCCCC2)C2C=CC=CC=2C2C(C(C)C)=CC(C(C)C)=CC=2C(C)C)CCCCC1.[O:35]1[CH2:40][CH2:39][N:38]([C:41]2[CH:42]=[C:43]([NH2:47])[CH:44]=[N:45][CH:46]=2)[CH2:37][CH2:36]1.Cl[C:49]1[C:58]2[C:53](=[C:54]([Cl:59])[CH:55]=[CH:56][CH:57]=2)[N:52]=[C:51]([C:60]2[CH:65]=[CH:64][CH:63]=[CH:62][N:61]=2)[C:50]=1[CH3:66].CC(C)([O-])C.[Na+]>C1(C)C=CC=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd]>[Cl:59][C:54]1[CH:55]=[CH:56][CH:57]=[C:58]2[C:53]=1[N:52]=[C:51]([C:60]1[CH:65]=[CH:64][CH:63]=[CH:62][N:61]=1)[C:50]([CH3:66])=[C:49]2[NH:47][C:43]1[CH:44]=[N:45][CH:46]=[C:41]([N:38]2[CH2:39][CH2:40][O:35][CH2:36][CH2:37]2)[CH:42]=1