2-Methoxy-8,9-dihydro-5H-benzo[7]annulen-6(7H)-one → 3-Methoxy-8-(4-methoxy-2-nitrophenyl)-6,7-dihydro-5H-benzocycloheptene

HRID 1433891ノート

反応式

HRID 1433891 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH2:12][C:11](=O)[CH2:10][CH2:9][CH2:8][C:7]=2[CH:14]=1.FC(F)(F)S(OC1CCCC2C=C(OC)C=CC=2C=1)(=O)=O.C([Sn](CCCC)(CCCC)[C:41]1[CH:46]=[CH:45][C:44]([O:47][CH3:48])=[CH:43][C:42]=1[N+:49]([O-:51])=[O:50])CCC>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:12]=[C:11]([C:41]3[CH:46]=[CH:45][C:44]([O:47][CH3:48])=[CH:43][C:42]=3[N+:49]([O-:51])=[O:50])[CH2:10][CH2:9][CH2:8][C:7]=2[CH:14]=1

参加物

4

反応物 3

HCID 123691772-Methoxy-8,9-dihydro-5H-benzo[7]annulen-6(7H)-oneHCID 23087474Tributyl(4-methoxy-2-nitrophenyl)tinHCID 86605238HCID 86605238、化合物

生成物 1

HCID 666269683-Methoxy-8-(4-methoxy-2-nitrophenyl)-6,7-dihydro-5H-benzocycloheptene

実験手順

Synthesized from 2-methoxy-5,7,8,9-tetrahydrobenzocyclohepten-6-one according to an analogous synthetic method to Preparation Example 82, 2-methoxy-8,9-dihydro-7H-benzocyclohepten-6-yl trifluoromethanesulfonate (3.0 g) and tributyl(4-methoxy-2-nitrophenyl)tin (10.8 g) were used according to an analogous synthetic method to Preparation Example 77 to provide the title compound (2.8 g).

後処理

  1. customwere used according to an analogous synthetic method to Preparation Example 77

出典と根拠

ORDレコード
ord-da2c626018c74dd2bd3ba753b6f2cbb0
出典データセット
uspto-grants-2009_11
特許番号
US07612114B2

反応ノート

読み込み中…