化工社化工社 化学情報印刷レポート · 研究参考用
Benzene, 4-bromo-1,2-dimethoxy- → 7-Benzyloxy-3-(4,5-dimethoxy-2-nitrophenyl)-1,2-dihydronaphthalene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzene, 4-bromo-1,2-dimethoxy- | HCID 76114 | — |
| 反応物 | 4-Bromo-5-nitroveratrole | HCID 170968 | — |
| 反応物 | 3-Bromo-1,2-dihydro-7-(phenylmethoxy)naphthalene | HCID 23087420 | — |
| 生成物 | 7-Benzyloxy-3-(4,5-dimethoxy-2-nitrophenyl)-1,2-dihydronaphthalene | HCID 23087426 | 21.8% |
反応手順
Synthesized from 1-bromo-3,4-dimethoxybenzene according to an analogous synthetic method to Preparation Example 108, 1-bromo-4,5-dimethoxy-2-nitrobenzene (7.5 g) and 7-benzyloxy-3-bromo-1,2-dihydronaphthalene (4.5 g) were used according to an analogous synthetic method to Preparation Example 107 to provide 7-benzyloxy-3-(4,5-dimethoxy-2-nitrophenyl)-1,2-dihydronaphthalene (1.3 g). The total amount of this compound was used according to an analogous synthetic method to Example 30 to provide the title compound (822 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07612114B2 |
| 出典データセット | uspto-grants-2009_11 |
| ORD ID | ord-c1bd0f8be5354add8b27466babec199f |
| 出典メモ | uspto-grants-2009_11 |