化工社化工社 化学情報印刷レポート · 研究参考用
Trifluoroacetic acid → L-Glutamic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | L-Glutamic acid di-tert-butyl ester | HCID 208637 | — |
| 反応物 | 2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborate | HCID 9857522 | — |
| 反応物 | Succinimidyl hexadecandioate | HCID 131727748 | — |
| 生成物 | L-Glutamic Acid | HCID 33032 | — |
反応手順
This compound was prepared in analogy with example 4, via reaction of L-Glu(OtBu)-OtBu with succinimidyl hexadecandioate followed by activation with TSTU, coupling with Des(B30) human insulin and deprotection by TFA. LCMS 6130.8, calculated 6132.2.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07615532B2 |
| 出典データセット | uspto-grants-2009_11 |
| ORD ID | ord-d1837f8ca0c74a208a5d17b723bb0257 |
| 出典メモ | uspto-grants-2009_11 |