2-Methyl-1-(thiophen-2-yl)propan-2-ol → 2-Methyl-1-{5-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-thiophen-2-yl}-propan-2-ol
反応式
Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]2)[N:3]=1.[CH3:19][C:20]([OH:28])([CH3:27])[CH2:21][C:22]1[S:23][CH:24]=[CH:25][CH:26]=1>>[CH3:19][C:20]([OH:28])([CH3:27])[CH2:21][C:22]1[S:23][C:24]([C:2]2[CH:7]=[CH:6][N:5]=[C:4]([NH:8][CH:9]3[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]3)[N:3]=2)=[CH:25][CH:26]=1参加物
3
実験手順
The title compound was prepared analogous to Method C, starting from (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine and 2-methyl-1-thiophen-2-yl-propan-2-ol.
出典と根拠
- ORDレコード
- ord-901a37fea3c04565b50e57c338a15e8d
- 出典データセット
- uspto-grants-2009_11