化工社化工社 化学情報印刷レポート · 研究参考用
4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl (2-{[(4-bromo-2,5-difluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Thiazoleacetic acid, 2-amino-, ethyl ester | HCID 104454 | — |
| 反応物 | 4-Bromo-2,5-difluorobenzenesulfonyl Chloride | HCID 574590 | — |
| 生成物 | Ethyl (2-{[(4-bromo-2,5-difluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate | HCID 10275050 | — |
反応手順
The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 4-bromo-2,5-difluorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (21.9 mg) with purity >90%. MS (pos) m/z 441.0, 443.0.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07618961B2 |
| 出典データセット | uspto-grants-2009_11 |
| ORD ID | ord-15fe492acbe34b05979d10fa7f3cc722 |
| 出典メモ | uspto-grants-2009_11 |