4-Chloro-2-methylquinazoline → N-(5-Methoxypyrazin-2-yl)-N,2-dimethylquinazolin-4-amine
反応式
[CH3:1][O:2][C:3]1[N:4]=[CH:5][C:6]([NH:9][C:10]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[N:13]=[C:12]([CH3:20])[N:11]=2)=[N:7][CH:8]=1.N[C:22]1C=NC(OC)=CN=1.ClC1C2C(=CC=CC=2)N=C(C)N=1>>[CH3:1][O:2][C:3]1[N:4]=[CH:5][C:6]([N:9]([C:10]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[N:13]=[C:12]([CH3:20])[N:11]=2)[CH3:22])=[N:7][CH:8]=1参加物
4
実験手順
(5-Methoxy-pyrazin-2-yl)-(2-methyl-quinazolin-4-yl)-amine: The title compound was prepared from 2-amino-5-methoxy-pyrazine (105 mg, 0.84 mmol) and 4-chloro-2-methyl-quinazoline (150 mg, 0.84 mmol) by a procedure similar to example 125c, yielding 106 mg of the title product.
出典と根拠
- ORDレコード
- ord-79b68bf820fd4f8cb405e008a125a3e6
- 出典データセット
- uspto-grants-2009_11
- 特許番号
- US07618975B2
反応ノート
読み込み中…