Hydrochloric Acid → HCID 91658617、化合物

HRID 1436376

反応式

HRID 1436376 の反応式
[ClH:1].[CH2:2]([O:4][C:5]([C:7]1([NH:10]C(OC(C)(C)C)=O)[CH2:9][CH2:8]1)=[O:6])[CH3:3]>C(OCC)(=O)C>[Cl-:1].[CH2:2]([O:4][C:5]([C:7]1([NH3+:10])[CH2:9][CH2:8]1)=[O:6])[CH3:3]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 10242916Ethyl 1-((tert-butoxycarbonyl)amino)cyclopropanecarboxylate

生成物 1

HCID 91658617HCID 91658617、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒2 回

実験手順

A saturated solution of HCl in ethyl acetate (20 mL) was added under nitrogen to a solution of 1-[[(1,1-dimethylethoxy)carbonyl]amino]cyclopropane carboxylic acid ethyl ester (10.07 g, 43.9 mmol), prepared in the previous step, in 20 mL of ethyl acetate at room temperature. After the addition, the reaction was stirred at room temperature for 1 h. The solid present was collected by filtration, rinsed with ethyl acetate and dried under reduced pressure to give 1-ethoxycarbonyl-cyclopropyl-ammonium chloride as a white solid.

後処理

  1. additionAfter the addition
  2. filtrationThe solid present was collected by filtration
  3. washrinsed with ethyl acetate
  4. customdried under reduced pressure

出典と根拠

ORDレコード
ord-147f78c6847047b6a58b7ae09f3f9b92
出典データセット
uspto-grants-2009_11
特許番号
US07618990B2

関連ノート

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