2-Ethenyl-5-nitropyridine → 6-Ethylpyridin-3-amine

HRID 1437216ノート

反応式

HRID 1437216 の反応式
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([CH:10]=[CH2:11])=[N:8][CH:9]=1)([O-])=O.[H][H]>C(O)C.[C].[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([CH2:10][CH3:11])=[N:8][CH:9]=1

参加物

5

反応物 2

HCID 230905502-Ethenyl-5-nitropyridineHCID 178418361HCID 178418361、化合物

生成物 1

HCID 138607296-Ethylpyridin-3-amine

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 702Ethanol溶媒

実験手順

10% Palladium-carbon (50% wet, 90 mg) was added to 5-nitro-2-vinylpyridine (450 mg) in ethanol (30 mL), followed by stirring in a hydrogen atmosphere at room temperature for 15 hours. The catalyst was removed from the reaction mixture by filtration. Subsequently, the solvent was evaporated under reduced pressure, to thereby give the title compound as an oily substance (359 mg, 98%).

後処理

  1. customThe catalyst was removed from the reaction mixture by filtration
  2. customSubsequently, the solvent was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-a416115830cf4a28b2528ea5ae593b4e
出典データセット
uspto-grants-2009_11
特許番号
US07622471B2

反応ノート

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