2-Chlorobenzaldehyde → (3-Amino-5-chloro-pyridin-2-yl)-(2-chloro-phenyl)-methanone

反応式

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[Cl:10][C:11]1[CH:12]=[C:13]([N+:18]([O-])=O)[C:14](I)=[N:15][CH:16]=1>>[NH2:18][C:13]1[C:14]([C:4]([C:3]2[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=2[Cl:1])=[O:5])=[N:15][CH:16]=[C:11]([Cl:10])[CH:12]=1

参加物

反応物 2

HCID 69962-Chlorobenzaldehyde

HCID 579421085-Chloro-2-iodo-3-nitropyridine

生成物 1

HCID 57942272(3-Amino-5-chloro-pyridin-2-yl)-(2-chloro-phenyl)-methanone

実験手順

(3-Amino-5-chloro-pyridin-2-yl)-(2-chloro-phenyl)-methanone was prepared from 2-chlorobenzaldehyde and 5-chloro-2-iodo-3-nitro-pyridine in three steps according to the general procedure for synthesis of 3-Amino-5-chloro-pyridin-2-yl aryl ketones. MS m/z: 267.0 (M+H).

出典と根拠

ORDレコード: ord-0504b6f5eea94be69c6cbb44a603079f
出典データセット: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07622583B2

反応ノート

読み込み中…