Methanol → HCID 136354592、化合物

HRID 1438695ノート

反応式

HRID 1438695 の反応式
OC1[C:3]2[CH:14]=[CH:13][CH:12]=[CH:11][C:4]=2[S:5][C:6]=1[C:7](=[NH:10])OC.[CH3:15][OH:16].[CH:17]([OH:20])([CH3:19])[CH3:18]>>[OH:16][C:15]1[C:3]2[CH:14]=[CH:13][CH:12]=[CH:11][C:4]=2[S:5][C:6]=1[C:7](=[NH:10])[O:20][CH:17]([CH3:19])[CH3:18]

参加物

4

反応物 3

HCID 887MethanolHCID 3776IsopropanolHCID 304079852947-34-9

生成物 1

HCID 136354592HCID 136354592、化合物

実験手順

20 g of methyl 3-hydroxy-benzo[b] thiophene-2-carboximidate (Example 1) are heated under reflux in 500 ml of isopropanol for three days. The methanol being formed is constantly distilled off by passing through a stream of nitrogen. Evaporation to dryness and recrystallization of the residue from ethyl acetate yields yellow crystals with an m.p. of 208° C.

後処理

  1. distillationis constantly distilled off
  2. customEvaporation
  3. customto dryness and recrystallization of the residue from ethyl acetate
  4. customyields yellow crystals with an m.p. of 208° C.

出典と根拠

ORDレコード
ord-aa17a417dc48429283d11be6c1334e15
出典データセット
uspto-grants-1977_11
特許番号
US04056526

反応ノート

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