Acetic Acid → HCID 21400228、化合物

HRID 1438700ノート

反応式

HRID 1438700 の反応式
[CH3:1][N:2]1[C:7](=[O:8])[NH:6][CH:5](SC)[N:4]([NH2:11])[C:3]1=[O:12].C(O)(=O)C.[CH3:17][NH2:18]>C(O)(C)C>[CH3:1][N:2]1[C:7](=[O:8])[NH:6][CH:5]([NH:18][CH3:17])[N:4]([NH2:11])[C:3]1=[O:12]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 6329MethylamineHCID 53642864HCID 53642864、化合物

生成物 1

HCID 21400228HCID 21400228、化合物収率 88%

試薬・触媒・溶媒 1

HCID 3776Isopropanol溶媒

実験手順

18.8 g (0.1 mole) of 1-methyl-3-amino-4-methylmercaptotetrahydro-1,3,5-triazine-2,6-dione (prepared according to Example 2) were idssolved in 200 ml of isopropanol with addition of 6 g of glacial acetic acid and a pinch of ptoluenesulphonic acid and the mixture was saturated with methylamine gas at room temperature. The batch was left to stand for about 10 hours and was evaporated in vacuo, and the resudue was recrystallized from isopropanol. 15 g (88%) of 1-methyl-3-amino-4-methylamino-tetrahydro-1,3,5-triazine2,6-dione were obtained as a colorless powder; melting point 225°-227° C.

後処理

  1. waitThe batch was left
  2. customwas evaporated in vacuo
  3. customthe resudue was recrystallized from isopropanol

出典と根拠

ORDレコード
ord-9033d03f3b2b4826a01a60825f5c1b9d
出典データセット
uspto-grants-1977_11
特許番号
US04056527

反応ノート

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