Acetic Anhydride → HCID 53964927、化合物

HRID 1438931ノート

反応式

HRID 1438931 の反応式
[CH3:1][O:2][C:3]([CH:5]1[C:13]2[C:8](=[CH:9][C:10]([C:15](=[O:22])[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[C:11]([OH:14])[CH:12]=2)[CH2:7][CH2:6]1)=[O:4].[C:23](OC(=O)C)(=[O:25])[CH3:24]>>[CH3:1][O:2][C:3]([CH:5]1[C:13]2[C:8](=[CH:9][C:10]([C:15](=[O:22])[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[C:11]([O:14][C:23](=[O:25])[CH3:24])[CH:12]=2)[CH2:7][CH2:6]1)=[O:4]

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 54109752HCID 54109752、化合物

生成物 1

HCID 53964927HCID 53964927、化合物

実験手順

A solution of 10 g of 5-benzoyl-6-hydroxy-indane-1-carboxylic acid methyl ester in 100 ml of acetic anhydride is heated to the reflux temperature for 4 hours under anhydrous conditions. It is then evaporated to dryness in vacuo. The evaporation residue is mixed with 200 ml of toluene and evaporated in vacuo. Distillation of the evaporation residue in a high vacuum gives, in the fraction boiling at 195°-200° C/0.06 /mm Hg, 5-benzoyl-6-acetoxy-indane-1-carboxylic acid methyl ester in the form of a colourless oil.

後処理

  1. customIt is then evaporated to dryness in vacuo
  2. additionThe evaporation residue is mixed with 200 ml of toluene
  3. customevaporated in vacuo
  4. distillationDistillation of the evaporation residue in a high vacuum

出典と根拠

ORDレコード
ord-387e321adbf940e7b75503054513a784
出典データセット
uspto-grants-1977_11
特許番号
US04057573

反応ノート

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