Thiocyanic Acid → 2-Imino-3-(2'-hydroxy-2'-phenylethyl)thiazolidine thiocyanate

関与物質

反応手順

A solution of 1-hydroxy-1-phenyl-2-ethyleniminoethane (16.3 g) in dioxan (35 ml) was added dropwise and with stirring at 0° C to an aqueous solution of thiocyanic acid (200 ml of 1N solution). After the addition the mixture was stirred in the cold for 1 hour. It was then heated under reflux for 1 hour and the solution cooled. The desired compound crystallised in 96% yield, m.p. 160° C.

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