Triethylamine → N-(2,2,6-trimethyl-2,3-dihydrobenzofuran-7-yl)hexadecaneamide

HRID 1439929

反応式

HRID 1439929 の反応式
[CH2:1]([C:17](Cl)=[O:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]C.[NH2:20][C:21]1[C:29]2[O:28][C:27]([CH3:31])([CH3:30])[CH2:26][C:25]=2[CH:24]=[CH:23][C:22]=1[CH3:32].C(N(CC)CC)C.C(=O)([O-])O.[Na+]>ClCCl>[CH3:30][C:27]1([CH3:31])[CH2:26][C:25]2[CH:24]=[CH:23][C:22]([CH3:32])=[C:21]([NH:20][C:17](=[O:18])[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[C:29]=2[O:28]1

参加物

6

反応物 4

HCID 8471TriethylamineHCID 516892Sodium BicarbonateHCID 3516438Heptadecanoyl ChlorideHCID 106073987-Amino-2,2,6-trimethyl-2,3-dihydrobenzofuran

生成物 1

HCID 10835676N-(2,2,6-trimethyl-2,3-dihydrobenzofuran-7-yl)hexadecaneamide

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A 171 mg amount of hexadecanecarboxylic acid chloride was added to a solution of 100 mg of 7-amino-2,2,6-trimethyl-2,3-dihydrobenzofuran and 63 mg of triethylamine in 2 ml of dichloromethane, and the mixture was stirred at room temperature for one hour. A 10 ml amount of a saturated sodium hydrogencarbonate solution was added thereto, and the mixture was extracted twice with 20 ml of ethyl acetate.

後処理

  1. extractionthe mixture was extracted twice with 20 ml of ethyl acetate

出典と根拠

ORDレコード
ord-b926b7ef2eaa4f22b4c8453c1d1c3211
出典データセット
uspto-grants-1996_03
特許番号
US05496853

関連ノート

読み込み中…