Methanol → 1-Methyl-3-n-propyl-2-iminoimidazolidin-4-one
反応式
I.[CH3:2][N:3]1[CH2:7][C:6](=[O:8])[N:5]([CH2:9][CH2:10][CH3:11])[C:4]1=[NH:12].CO.[OH-].[K+]>>[CH3:2][N:3]1[CH2:7][C:6](=[O:8])[N:5]([CH2:9][CH2:10][CH3:11])[C:4]1=[NH:12]参加物
4
実験手順
2.83 g (10 mmol) of the 1-methyl-3-n-propyl-2-iminoimidazolidin-4-one hydroiodide was added to 25 ml of methanol containing 0.66 g (10 mmol) of 85% potassium hydroxide, and the mixture was stirred at room temperature for one hour. Methanol was distilled off under reduced pressure, and chloroform was added to the residue. Precipitated crystals were removed by filtration. Chloroform was distilled off under reduced pressure to obtain 1.16 g of 1-methyl-3-n-propyl-2 -iminoimidazolidin-4-one as an oily substance.
後処理
- distillationMethanol was distilled off under reduced pressure, and chloroform
- additionwas added to the residue
- customPrecipitated crystals
- customwere removed by filtration
- distillationChloroform was distilled off under reduced pressure
出典と根拠
- ORDレコード
- ord-c08634c764ad4bdbb610fbcbf4502dd7
- 出典データセット
- uspto-grants-1996_03
- 特許番号
- US05500406
反応ノート
読み込み中…