2-Methylimidazole → 4-(2-Methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzonitrile
反応式
Cl[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11].[CH3:14][C:15]1[NH:16][CH:17]=[CH:18][N:19]=1>>[CH3:14][C:15]1[N:16]([C:2]2[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=2[C:10]([F:13])([F:12])[F:11])[CH:17]=[CH:18][N:19]=1参加物
3
実験手順
The title compound is prepared using an analogous method as described in Example 1.1, utilising 4-chloro-3-(trifluoromethyl)-benzonitrile (Lancaster Synthesis GmbH) and 2-methyl-imidazole (Fluka, Buchs, Switzerland), with a reaction temperature of 145° C. for 38 hours.
出典と根拠
- ORDレコード
- ord-147df7f93a424152b8f8e11694aed57b
- 出典データセット
- uspto-grants-2010_02
- 特許番号
- US07655669B2
反応ノート
読み込み中…