Benzyl 2-amino-2-methylpropanoate hydrochloride → Benzyl 2-amino-2-methylpropanoate
反応式
Cl.[NH2:2][C:3]([CH3:15])([CH3:14])[C:4]([O:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:5]>C(OCC)(=O)C>[NH2:2][C:3]([CH3:15])([CH3:14])[C:4]([O:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:5]参加物
3
実験手順
Benzyl 2-amino-2-methylpropionate hydrochloride (1.48 g) was dissolved in ethyl acetate (60 mL) and a saturated aqueous sodium hydrogen carbonate solution (20 mL), and the organic layer was separated. The organic layer was washed with brine, and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure to give the title compound (1.2 g).
後処理
- customa saturated aqueous sodium hydrogen carbonate solution (20 mL), and the organic layer was separated
- washThe organic layer was washed with brine
- dry with materialdried over anhydrous magnesium sulfate
- customThe solvent was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-79df1b56083d4695b53e2b612188dd52
- 出典データセット
- uspto-grants-2010_02
- 特許番号
- US07655632B2
反応ノート
読み込み中…