Ammonia → 4-Hydroxy-2,6-dimethylnicotinic acid
反応式
[CH3:1][C:2]1O[C:4]([CH3:12])=[CH:5][C:6](=[O:11])[C:7]=1[C:8]([OH:10])=[O:9].[NH3:13]>Cl>[CH3:1][C:2]1[N:13]=[C:4]([CH3:12])[CH:5]=[C:6]([OH:11])[C:7]=1[C:8]([OH:10])=[O:9]参加物
4
実験手順
10 g (59.5 mmol) of 2,6-dimethyl-4-oxo-4H-pyran-3-carboxylic acid (prepared according to the method described in Collie, J. Chem. Soc.; 1907; 787) is stirred in 100 ml of 28% aqueous ammonia at room temperature overnight. The residue is diluted with little aqueous HCl, and the solid is filtered off. There is obtained 6.9 g (69% yield) of a solid.
後処理
- filtrationthe solid is filtered off
出典と根拠
- ORDレコード
- ord-a39137ede5c94218b3f9b600edc53846
- 出典データセット
- uspto-grants-2010_02
- 特許番号
- US07659307B2
反応ノート
読み込み中…