4-Bromo-2-methylpyridine → HCID 16661052、化合物
反応式
Cl[C:2]1[C:7]2[N:8]=[C:9]([CH3:11])[S:10][C:6]=2[C:5](B(O)O)=[CH:4][N:3]=1.Br[C:16]1[CH:21]=[CH:20][N:19]=[C:18]([CH3:22])[CH:17]=1.[NH2:23][C:24]1[N:25]=[C:26]([CH3:29])[S:27][CH:28]=1>>[CH3:11][C:9]1[S:10][C:6]2[C:5]([C:16]3[CH:21]=[CH:20][N:19]=[C:18]([CH3:22])[CH:17]=3)=[CH:4][N:3]=[C:2]([NH:23][C:24]3[N:25]=[C:26]([CH3:29])[S:27][CH:28]=3)[C:7]=2[N:8]=1参加物
4
実験手順
The title compound, MS: m/e=354.1 (M+H+), was prepared in accordance with the general method of example 2, step 1 and step 2 from 4-chloro-2-methyl-thiazolo[4,5-c]pyridine-7-boronic acid (Example D), 4-bromo-2-methylpyridine and 4-amino-2-methylthiazole (Example C).
出典と根拠
- ORDレコード
- ord-48eba57925e744959f77395c1f7da0be
- 出典データセット
- uspto-grants-2010_02
- 特許番号
- US07659401B2
反応ノート
読み込み中…