Citric Acid → HCID 13785667、化合物
反応式
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([O:11]S(C=C)(=O)=O)=[C:4]([CH3:17])[CH:3]=1.C(=O)([O-])[O-].[K+].[K+].C(O)(=O)CC(CC(O)=O)(C(O)=O)O>O.C(O)C>[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([OH:11])=[C:4]([CH3:17])[CH:3]=1参加物
5
実験手順
A solution of compound 106 (27.8 g, 100 mmol) and potassium carbonate (27.6 g, 200 mmol) in ethanol water 1/1 (600 ml) was refluxed for one hour. Citric acid (5%) was added and the mixture was extracted three times with DCM. The organic phase was dried with sodium sulphate and evaporated under reduced pressure which gave the title compound (19 g, 100%).
後処理
- extractionthe mixture was extracted three times with DCM
- dry with materialThe organic phase was dried with sodium sulphate
- customevaporated under reduced pressure which
出典と根拠
- ORDレコード
- ord-0554f642280a486ab7d1c16edd532465
- 出典データセット
- uspto-grants-2010_02
- 特許番号
- US07659245B2
反応ノート
読み込み中…