反応式
[Cl-:1].[NH3+:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([C:9]1[CH:10]=[NH+:11][CH:12]=[CH:13][CH:14]=1)=O.[Cl-].[C:16]1([C:22]2[O:26][C:25]([CH:27]=O)=[CH:24][CH:23]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C(O)(C)C>[ClH:1].[ClH:1].[C:16]1([C:22]2[O:26][C:25]([CH:27]=[C:6]3[CH2:5][CH2:4][CH2:3][N:2]=[C:7]3[C:9]3[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=3)=[CH:24][CH:23]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1参加物
4
反応条件
- 温度
- 85 °C
実験手順
3-(5-Ammoniopentanoyl)pyridinium chloride (188 mg, 0.75 mmol) was transferred to a reaction vessel and treated with isopropanol (12 mL). 5-Phenyl-2-furaldehyde (193 mg, 1.12 mmol) was added, the reaction vessel was sealed, and the reaction was heated to 85° C. with stirring for 6 hours. The reaction was then cooled to room temperature, and the precipitate was recovered by vacuum filtration, washed with isopropanol and ether then dried under vacuum giving 264 mg (91%) of an orange solid. LC-MS: RT=5.15 min, [M+H]+=315.1.
後処理
- customthe reaction vessel was sealed
- temperatureThe reaction was then cooled to room temperature
- filtrationthe precipitate was recovered by vacuum filtration
- washwashed with isopropanol and ether
- customthen dried under vacuum
出典と根拠
- ORDレコード
- ord-f1655f4472fc408f818e0e0d683a4319
- 出典データセット
- uspto-grants-2010_02
- 特許番号
- US07662965B2
関連ノート
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