Acetyl chloride → HCID 18613788、化合物

反応式

[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([CH2:6][CH2:7][NH2:8])=[CH:4][CH:3]=1.[C:11](Cl)(=O)[CH3:12]>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][NH:8][CH:11]2[CH3:12])=[CH:4][CH:3]=1

参加物

反応物 2

HCID 6367Acetyl chloride

HCID 674302-(4-Chlorophenyl)ethylamine

生成物 1

HCID 18613788HCID 18613788、化合物

実験手順

In accordance with the same procedures as in Steps 1, 2, and 3 of Preparation 21, except for using 4-chlorophenethylamine and acetyl chloride, 7-chloro-1-methyl-1,2,3,4-tetrahydroisoquinoline was obtained. In accordance with the same procedures as in Preparation 20, the titled compound was obtained as pale yellow oil. (Yield: 67%) The product was used in the subsequent step without further purification.

後処理

customIn accordance with the same procedures as in Steps 1, 2, and 3 of Preparation 21

出典と根拠

ORDレコード: ord-79b7ec8d86c74cffa1053ecf3fd90a07
出典データセット: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07662832B2

反応ノート

読み込み中…